What is colchicine (Colcrys)?

Colchicine affects the way the body responds to uric acid crystals, which reduces swelling and pain. Generic forms of colchicine have been used to treat or prevent attacks of gout or to treat symptoms of Behcet’s syndrome (such as swelling, redness, warmth, and pain). Colchicine is not a cure for gouty arthritis or Behcet’s syndrome, and it will not prevent these diseases from progressing. Colchicine should not be used as a routine pain medication for other conditions.

Side effects of colchicine

  • muscle pain or weakness;
  • numbness or tingly feeling in your fingers or toes;
  • pale or gray appearance of your lips, tongue, or hands;
  • severe vomiting or diarrhea;
  • easy bruising or bleeding, feeling weak or tired;
  • fever, chills, body aches, flu symptoms;
  • blood in your urine; or
  • urinating less than usual or not at all.

Less serious side effects may include:

  • mild nausea or vomiting, stomach pain; or
  • mild diarrhea.

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